徐曉飛
基本信息
學(xué)位:工學(xué)博士
學(xué)術(shù)/專(zhuān)業(yè)學(xué)位碩士研究生導(dǎo)師
E-mail： [email protected]
通訊地址廣東省陽(yáng)江市江城區(qū)羅琴路1號(hào)海科樓402A
個(gè)人簡(jiǎn)介
1979年生，博士后、高級(jí)工程師，現(xiàn)任廣東海洋大學(xué)食品科學(xué)與工程學(xué)院教師，曾任無(wú)限極(中國(guó))有限公司研發(fā)高級(jí)主任、仙樂(lè)健康科技股份有限公司研發(fā)高級(jí)經(jīng)理、華南協(xié)同創(chuàng)新研究院生物活性分子開(kāi)發(fā)與應(yīng)用創(chuàng)新中心副主任。先后主持博士后科學(xué)基金（面上項(xiàng)目和特別資助）、中央高?；究蒲袠I(yè)務(wù)經(jīng)費(fèi)項(xiàng)目、省科技專(zhuān)項(xiàng)和企業(yè)橫向課題等十余項(xiàng)。主講課程為食品化學(xué)、保健食品原理與功能評(píng)價(jià)、創(chuàng)新創(chuàng)業(yè)和食品工廠(chǎng)設(shè)計(jì)。在企業(yè)逾20年?duì)I養(yǎng)補(bǔ)充劑及保健食品/功能食品研發(fā)經(jīng)驗(yàn)，擅長(zhǎng)天然活性成分挖掘與產(chǎn)業(yè)化開(kāi)發(fā)，已開(kāi)發(fā)上市營(yíng)養(yǎng)保健/功能食品逾六十余款，年銷(xiāo)售額過(guò)百億元，代表性產(chǎn)品有無(wú)限極增健口服液、無(wú)限極源適餐粉/源樂(lè)餐粉、無(wú)限極元泰片、千林檸檬酸鈣片以及維樂(lè)維營(yíng)養(yǎng)軟糖系列、燃小乙體重管理產(chǎn)品、UKDNA銀耳膠原蛋白肽、繡球菌濃縮凍干片等，申請(qǐng)專(zhuān)利20余項(xiàng)（授權(quán)中國(guó)專(zhuān)利18項(xiàng)，美國(guó)專(zhuān)利1項(xiàng)），主導(dǎo)開(kāi)發(fā)獲批功能性中草藥保健食品批文10項(xiàng)，參編并主持開(kāi)發(fā)兩項(xiàng)功能食品因子多糖檢測(cè)方法入編《保健食品功效成分檢測(cè)方法》書(shū)籍，發(fā)表國(guó)內(nèi)外學(xué)術(shù)期刊論文70余篇。
研究方向
1.食用菌來(lái)源（香菇、茯苓、銀耳、繡球菌等）天然多糖的結(jié)構(gòu)、功能和機(jī)理研究
2.藥食同源資源的產(chǎn)業(yè)化開(kāi)發(fā)、深加工技術(shù)研究
3.特色鮮明的保健食品、功能食品、營(yíng)養(yǎng)補(bǔ)充劑等食品開(kāi)發(fā)、產(chǎn)品功效及機(jī)理研究
4.多糖原料、功能/保健食品中多糖檢測(cè)方法研究
主持/參與科研項(xiàng)目
1.廣東省科學(xué)技術(shù)廳，2022省科技專(zhuān)項(xiàng)資金（“大專(zhuān)項(xiàng)+任務(wù)清單”）項(xiàng)目—陽(yáng)江山藥深加工產(chǎn)業(yè)化技術(shù)研究與產(chǎn)品開(kāi)發(fā)
2.廣東省科學(xué)技術(shù)廳，廣東省重點(diǎn)領(lǐng)域研發(fā)計(jì)劃—食品控糖降脂活性成分結(jié)構(gòu)解析、定向富集和產(chǎn)業(yè)化應(yīng)用 2021B0707060001
3.科技部，2018年國(guó)家重點(diǎn)研發(fā)計(jì)劃“食品安全關(guān)鍵技術(shù)研發(fā)”重點(diǎn)專(zhuān)項(xiàng)子課題2018YFC1602102，保健食品生產(chǎn)加工過(guò)程風(fēng)險(xiǎn)評(píng)價(jià)技術(shù)
4.中國(guó)博士后科學(xué)基金會(huì)，第九批博士后科學(xué)基金特別資助，2016T90787
5.華南理工大學(xué)中央高?？蒲薪?jīng)費(fèi)自然科學(xué)項(xiàng)目，2015ZM164
6.中國(guó)博士后科學(xué)基金會(huì)，第57批面上資助，2015M572324
7.企業(yè)橫向項(xiàng)目：功能食品和日化產(chǎn)品開(kāi)發(fā)；
8.企業(yè)橫向項(xiàng)目：繡球菌功能食品開(kāi)發(fā)與產(chǎn)業(yè)化；
9.企業(yè)橫向項(xiàng)目：食用菌多糖工藝開(kāi)發(fā)
主要論文
1. Xu Xiaofei*, Liu Xiaofei, Liu Liyan, Chen Jin, Guan Jingjing, Luo Donghui. Metagenomic and transcriptomic profiling of the hypoglycemic and hypotriglyceridemic actions ofTremella fuciformis-derived polysaccharides in high-fat-diet- and streptozotocin-treated mice. Food&Function. 2024, 15(22):11096-11114.
2. Xu Yuanyuan, Xiaofei Liu, Jingjing Guan, Jin Chen,Xiaofei Xu*. iTRAQ-Based Proteomic Profiling of Skin Aging Protective Effects ofTremella fuciformis-Derived Polysaccharides on D-Galactose-Induced Aging Mice, Molecules,2024. 29, no. 21: 5191.
3.徐曉飛,陳萌,謝英潔,吳豐魏.基于iTRAQ蛋白質(zhì)組學(xué)技術(shù)分析羧甲基茯苓多糖對(duì)老齡小鼠免疫功能和血脂調(diào)節(jié)的機(jī)理.食品科學(xué)技術(shù)學(xué)報(bào)，2024，42(6):54 -67.
4.葉鵬,徐曉飛*,何瑞琪.繡球菌功能食品對(duì)敏感性皮膚人群的作用研究.食用菌,2024,46（2）：66-72.
6. Luo Donghui, Liu Xiaofei, Guan Jinjin, Chen Jin,Xu Xiaofei*. Effects ofTremella fuciformis-derived polysaccharides with different molecular weight on D-galactose-induced aging of mice. Polish Journal of Food and Nutrition Sciences. 2023;73(2):163-174.
7. Luo Donghui, Zhang Xuewu,Xu Xiaofei*.1H NMR-based urinary metabolic analysis of high-dose cyclophosphamide-induced toxicity in mice. Analytical Biochemistry. 2023, 670:115138.
8.徐媛媛,陳萌,徐曉飛*,何瑞琪.繡球菌濃縮液抑制黑色素合成和抗氧化活性研究.食品安全質(zhì)量檢測(cè)學(xué)報(bào), 2023, 14(17):261-268.
9.徐曉飛，何瑞琪，宗敏華，羅東輝，邱樹(shù)毅.紅曲霉代謝產(chǎn)物的調(diào)控及在釀酒中的應(yīng)用研究進(jìn)展.中國(guó)釀造, 2023, 42(4): 8-13.
10.徐曉飛,羅東輝,趙明月,鐘興偉.兩種銀耳多糖對(duì)小鼠抗衰作用的比較.食用菌學(xué)報(bào). 2022, 38 (02): 93-102.
11.徐曉飛,趙明月,鐘興偉等.膠原蛋白肽復(fù)合銀耳多糖對(duì)D-半乳糖致衰小鼠的改善作用.中國(guó)食品學(xué)報(bào), 2022, 22(10):134-142.
12. Liu Xiaofei, Luo Donghui, Guan Jinjin, Chen Jin,Xu Xiaofei*. Mushroom polysaccharides with potential in anti-diabetes: Biological mechanisms, extraction, and future perspectives: A review. Frontiers in Nutrition. 2022; 9:1087826.
13. Luo Donghui, Guan Jingjing, Dong Hao*, Chen Jin, Liang Ming, Zhou Chunxia, Xian Yanpin,Xu Xiaofei*. Simultaneous determination of twelve mycotoxins in edible oil, soy sauce and bean sauce by PRiME HLB solid phase extraction combined with HPLC-Orbitrap HRMS. Frontiers in Nutrition. 2022; 9:1001671.
14.徐曉飛，鐘興偉，趙明月，何瑞琪.膠原蛋白肽與銀耳多糖對(duì)衰老小鼠皮膚改善作用及機(jī)理研究.食品工業(yè)科技，2022，43（8）：357?364.
15.劉星汶,楊繼國(guó),徐曉飛*.羧甲基茯苓多糖的水媒法制備及其免疫活性研究.菌物學(xué)報(bào), 2021, 40(6): 1575-1582.
16.何瑞琪,趙明月,鐘興偉,徐曉飛*.含膠原蛋白肽飲品對(duì)衰老小鼠皮膚改善作用和抗氧化作用研究.食品安全質(zhì)量檢測(cè)學(xué)報(bào), 2021, 12(19):8.
17. Liu Xiaofei, Wang Xiaoqin,Xu Xiaofei, Zhang Xuewu. Purification, antitumor and anti-inflammation activities of an alkali-soluble and carboxymethyl polysaccharide CMP33 fromPoria cocos. International Journal of Biological Macromolecules, 2019, 127: 39-47.
18.徐曉飛,陳慧萍,楊繼國(guó).兒童消化系統(tǒng)發(fā)育生理研究進(jìn)展.中國(guó)兒童保健雜志, 2019, 27(11):1196-1200.
19. Liu Xiaofei, Yu Xiuting,Xu Xiaofei, Zhang Xuewu. The protective effects ofPoria cocos-derived polysaccharide CMP33 against IBD in mice and its molecular mechanism. Food & Function, 2018, 9(11): 5936-5949.
20.徐曉飛,鐘浩權(quán),劉瑋,夏晚霞,楊繼國(guó).體外模擬消化維生素C和鈣軟糖的動(dòng)力學(xué)研究.現(xiàn)代食品科技, 2018, 34(11):89-94+280.
21.徐曉飛,鐘浩權(quán),夏晚霞,劉瑋,楊繼國(guó).體外模擬消化多維鋅軟糖的研究.中國(guó)食品添加劑, 2018, 11:162-168.
22. Xu Xiaofei, Yang Jiguo, Ning Zhengxiang, Zhang Xuewu.1H NMR-based metabolic profiling of urine from mice fedLentinula edodes-derived polysaccharides. Polish Journal of Food and Nutrition Sciences. 2018;68(3):207–216.
23. Xu Xiaofei, Yang Jiguo, Ning Zhengxian, Zhang Xuewu.1H NMR-based metabolic investigation of the effect ofLentinula edodes-derived polysaccharides on aged mice. Journal of Food Biochemistry. 2017. 41:e12371.
24. Xu Xiaofei, Yang Jiguo, Ning Zhengxian, Zhang Xuewu. Proteomic analysis of intestinal tissues from mice fed1withLentinula edodes-derived polysaccharides. Food & Function. 2016. 7(1)：250-261.
25. Xu Xiaofei, Wang Zhujun, Zhang Xuewu. The human microbiota associated with overall health. Critical Reviews in Biotechnology. 2015, 35(1):129-140
26. Xu Xiaofei, Zhang Xuewu.Lentinula edodes-derived polysaccharide alters the spatial structure of gut microbiota in mice. PLoS One, 2015,10(1): e0115037
27. Xu Xiaofei, Yang Jiguo, Luo Zhen, Zhang Xuewu.Lentinula edodes-derived polysaccharide enhances systemic and mucosal immunity by spatial modulation of intestinal gene expression in mice. Food & Function, 2015, 6:2068-2080.
28. Xu Xiaofei, Yang Jiguo, Ning Zhengxian, Zhang Xuewu.Lentinula edodes-derived polysaccharide rejuvenates mice in terms of immune responses and gut microbiota. Food & Function, 2015, 6(8):2653-63.
29. Xu Xiaofei, Zhang Xuewu. Effects of cyclophosphamide on immune system and gut microbiota in mice. Microbiological Research. 2015, 171:97–106.
30. Xu Xiaofei, Yan Huidang, Tang Jian, Chen Jian, Zhang Xuewu. Polysaccharides inLentinus edodes: Isolation, structure, immuno-modulating activity and future prospective. Critical Reviews in Food Science and Nutrition. 2014; 54(4):474-87.
31. Xu Xiaofei, He Shengjie, Zhang Xuewu. New food safety concerns associated with gut microbiota. Trends in Food Science and Technology. 2013, 34(1): 62-66.
32. Xu Xiaofei, Xu Pingping, Zhang Xuewu. Gut Microbiota, Host Health and Polysaccharides. Biotechnology Advances. 2013. 31,318-37.
33. Xu Xiaofei, Yan Huidang, Zhang Xuewu. Structure and immuno-stimulating activities of a new heteropolysaccharide fromLentinula edodes. Journal Agricultural and Food Chemistry 2012.60, 11560-11566.
34. Xu Xiaofei, Yan Huidang, Chen Jian, Zhang. Xuewu. Bioactive proteins from mushrooms. Biotechnology Advances. 2011. 29,667-674
35.徐曉飛，張丙青，羅珍，陳健.不同產(chǎn)地香菇營(yíng)養(yǎng)成分的比較研究，食用菌，2012，32:57.
36.徐曉飛，向瑩，張小爽，陳健.不同干燥方式對(duì)香菇品質(zhì)的影響[J].食品工業(yè)科技，2012，17:259.
37.徐曉飛，閆慧丹，羅珍，張學(xué)武.香菇多糖Lentinan的提取分離、生物活性和構(gòu)效關(guān)系的研究進(jìn)展.食品工業(yè)科技. 2012, 33:435.
38.徐曉飛，羅珍.多糖類(lèi)保健品質(zhì)量控制技術(shù)的研究進(jìn)展.中國(guó)食物與營(yíng)養(yǎng). 2011. 9:18-20;
39.陳健,張靈芝,韋丁,徐曉飛.黑虎掌菌多糖的組成和抗腫瘤活性[J].華南理工大學(xué)學(xué)報(bào)(自然科學(xué)版), 2011, 39(12):110-114.
獲獎(jiǎng)
1.紅曲醬香白酒，中國(guó)食品工業(yè)協(xié)會(huì)科學(xué)技術(shù)一等獎(jiǎng)，2022
2.氧沁多糖刺梨生物發(fā)酵飲品，中國(guó)食品工業(yè)協(xié)會(huì)科學(xué)技術(shù)一等獎(jiǎng)，2020
3.中草藥活性多糖快速篩選、制備關(guān)鍵技術(shù)及產(chǎn)業(yè)化應(yīng)用，江門(mén)市科學(xué)技術(shù)獎(jiǎng)特等獎(jiǎng)，2014.
